Completed

Occupational exposure to diesel and gasoline emissions and the risk of colorectal and bladder cancer

Purpose

The purpose of this study was to examine whether workplace exposures to diesel and gasoline emissions increase the risk of developing colorectal and bladder cancer among Canadian men.

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Significance

Workplace exposures to diesel and gasoline emissions from engine exhausts are known to affect human health, but their effects on cancer remain poorly understood. Exposure to diesel and gasoline exhaust is common among Ontario workers, and it has been estimated that more than 230,000 Ontario workers are exposed to some degree.

Methods

This study compared workplace exposures among a sample of Canadian men who developed these cancers to a group of men who were cancer-free. All jobs held over the lifetime of each participant were assessed according to the level of exposure and the percentage of time that exposure occurred. Other factors that may have had an effect on the development of these types of cancers, such as age, cigarette smoking, diet, physical activity and other workplace exposures, were taken in account.

Implications

This research has the potential to reduce occupational cancer. In the presence of a real association between diesel and gasoline emissions and bladder and colorectal cancers, there are interventions that could be implemented to reduce workers’ exposures to these emissions.

Results
  • Bladder cancer and occupational exposure to diesel and gasoline engine emissions among Canadian men

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  • Workplace exposure to diesel and gasoline engine exhausts and the risk of colorectal cancer in Canadian men

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Research Team
Shelley Harris (PI)
OCRC, University of Toronto
Paul Villeneuve
Health Canada, University of Toronto
Linda Kachuri
OCRC
Kenneth Johnson
Public Health Agency of Canada
Marie-Élise Parent
Institut national de la recherché scientifique