Asbestosis

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Background

Asbestosis is a chronic lung disease caused by inhalation of asbestos fibers. Exposure to these fibers can cause lung tissue scarring and shortness of breath. Asbestosis can develop many decades after exposure to asbestos.

Risk factors

  • Asbestos fibres (all types) [1]

Construction workers, such as insulators, electricians, and plumbers are several occupations that have experienced high rates of this condition. Metal workers and platers and boilermakers are also at an increased risk of asbestosis.

Key Findings

The greatest risks of asbestosis were observed among workers employed in construction and some manufacturing industries.

Construction

Asbestos-containing materials, particular insulation, were widely used in pre-1990 construction in Canada, and is still present in many older homes and buildings [2]. Insulators, plumbers, electricians, and other construction trades workers may frequently handle or work near asbestos-containing materials during building maintenance and renovation.

  • Construction trades occupations: 3.50 times the risk
    • Insulators: 25.4 times the risk
    • Pipefitters and plumbers: 8.36 times the risk
    • Plasterers and related: 5.38 times the risk
    • Brick and stone masons and tile setters: 3.76 times the risk
    • Electricians and repairers: 3.35 times the risk
    • Carpenters and related: 2.05 times the risk
Non-Metallic Mineral Products Manufacturing

The non-metallic mineral products industry includes establishments engaged in manufacturing clay, cement and concrete, glass and glass products, and historically, asbestos and vermiculite products. The latter manufacturers are captured in the miscellaneous non-metallic mineral products industries, where the highest asbestosis risk was observed.

  • Non-metallic mineral products industries: 2.14 times the risk
    • Miscellaneous non-metallic mineral products: 7.56 times the risk
Metal-Related Industries and Occupations

Asbestos was commonly used as an insulating material in some hot metalworking processes [3]. Primary metal industry workers may operate furnaces and other heating apparatuses insulated with asbestos. When these materials are disturbed or degrade, asbestos fibres can be released into the air.

  • Boilermakers, platers and structural metal workers: 9.96 times risk
  • Sheet metal workers: 2.44 times the risk
  • Primary metal industries: 2.34 times the risk
    • Iron and steel mills: 2.77 times the risk
Mechanics and Repairers Except Electrical

Mechanics work on maintenance and repair of machinery and vehicles, which often involves removing parts for cleaning or replacement. Asbestos was widely used in auto parts, such as brake pads, clutches, and hoodliners, and may be present in older vehicles and machinery [4,5].

  • Industrial, farm and construction machinery mechanics and repairers: 1.52 times the risk
Rubber and Plastics Manufacturing

Increased AMI risk was observed among workers in the ODSS employed in rubber and plastic products fabrication. Plastic stabilizers frequently include cadmium, which has been posited to increase AMI risk through atherosclerosis [21]. A cohort study of British rubber factory workers found increased risk of cardiovascular deaths associated with exposure to N-nitrosomorpholine, rubber dust, rubber fumes and N-nitrosamines sum [22].

  • Occupations in labouring and other elemental work: fabricating, assembling and repairing, rubber, plastic and related products: 1.91 times the risk
  • Bonding and cementing occupations, rubber, plastic and related products: 1.40 times the risk
Other Groups

Excess AMI risk was detected in the ODSS for a variety of occupation groups, which likely reflects the numerous risk factors for cardiovascular disease including both workplace and lifestyle factors.

  • Receptionists and information clerks: 1.62 times the risk
  • Fish canning, curing and packing occupations: 1.52 times the risk
  • Truck drivers: 1.32 times the risk

For more details: Troke, N, Logar‐Henderson, C, DeBono, N, et al. Incidence of acute myocardial infarction in the workforce: findings from the Occupational Disease Surveillance System. Am J Ind Med. 2021; 1– 20.

Relative Risk by Industry and Occupation

 

 

 

 

Figure 1. Risk of asbestosis diagnosis among workers employed in each industry group relative to all others, Occupational Disease Surveillance System (ODSS), 1999-2016

The hazard ratio is an estimate of the average time to diagnosis among workers in each industry/occupation group divided by that in all others during the study period. Hazard ratios above 1.00 indicate a greater risk of disease in a given group compared to all others. Estimates are adjusted for birth year and sex. The width of the 95% Confidence Interval (CI) is based on the number of cases in each group (more cases narrows the interval).

Figure 2. Risk of asbestosis diagnosis among workers employed in each occupation group relative to all others, Occupational Disease Surveillance System (ODSS), 1999-2016 

The hazard ratio is an estimate of the average time to diagnosis among workers in each industry/occupation group divided by that in all others during the study period. Hazard ratios above 1.00 indicate a greater risk of disease in a given group compared to all others. Estimates are adjusted for birth year and sex. The width of the 95% Confidence Interval (CI) is based on the number of cases in each group (more cases narrows the interval).

Table of Results

Table 1. Surveillance of Asbestosis: Number of cases, workers employed, and hazard ratios in each industry (SIC)

 SIC Code *  Industry Group  Number of cases  Number of workers employed  Hazard Ratio (95% CI) †
 1  Agriculture  <5  27,818  —
 2/3  Forestry, Fishing and Trapping  0  7,857  —
 4  Mines, Quarries and Oil Wells  13  18,210  0.99 (0.57-1.72)
 5  Manufacturing  243  565,700  0.95 (0.81-1.11)
 6  Construction  153  175,617  2.35 (1.95-2.82)
 7  Transportation, Communication and Other Utilities  66  165,930  0.94 (0.73-1.21)
 8  Trade  52  357,376  0.46 (0.35-0.62)
 9  Finance, Insurance and Real Estate  11  19,414  1.28 (0.70-2.32)
 10  Community, Business and Personal Service  98  483,986  0.86 (0.69-1.07)
 11  Public Administration and Defense  63  157,922  0.95 (0.73-1.23)
 * SIC: Standard Industrial Classification (1970)
 † Hazard ratio in each group relative to all others

Table 2. Surveillance of Asbestosis: Number of cases, workers employed, and hazard ratios in each occupation (CCDO) group

 CCDO Code *  Occupation Group  Number of cases  Number of workers employed  Hazard Ratio (95% CI) †
 11  Managerial, administrative and related  5  26,772  0.61 (0.25-1.48)
 21  Natural sciences, engineering and mathematics  8  22,785  0.92 (0.46-1.84)
 23  Social sciences and related fields  5  24,939  1.56 (0.64-3.77)
 25  Religion  0  113  —
 27  Teaching and related  8  41,692  1.03 (0.51-2.09)
 31  Medicine and health  10  108,759  0.66 (0.35-1.26)
 33  Artistic, literary, recreational and related  <5  12,729  —
 41  Clerical and related  23  162,132  0.51 (0.34-0.77)
 51  Sales  22  123,283  0.86 (0.56-1.31)
 61  Service  62  298,287  0.66 (0.51-0.86)
 71  Farming, horticultural and animal husbandry  5  40,974  0.39 (0.16-0.93)
 73  Fishing, hunting, trapping and related  0  463  —
 75  Forestry and logging  0  7,730  —
 77  Mining and quarrying, including oil and gas field  6  10,079  0.86 (0.39-1.93)
 81  Processing (mineral, metal, chemical)  37  67,239  1.45 (1.04-2.02)
 82  Processing (food, wood, textile)  18  81,535  0.65 (0.41-1.04)
 83  Machining and related  76  161,878  0.99 (0.78-1.26)
 85  Product fabricating, assembling and repairing  107  276,755  0.84 (0.69-1.04)
 87  Construction trades  230  181,331  3.50 (2.97-4.13)
 91  Transport equipment operating  40  143,836  0.58 (0.42-0.79)
 93  Materials handling and related, not elsewhere classified  19  128,517  0.40 (0.25-0.63)
 95  Other crafts and equipment operating  190  23,406  0.91 (0.49-1.69)
 99  Other occupations not elsewhere classified  55  180,646  0.81 (0.62-1.07)
 * CCDO: Canadian Classification Dictionary of Occupations (1971)
 † Hazard ratio in each group relative to all others

Please note that ODSS results shown here may differ from those previously published or presented. This may occur due to changes in case definitions, methodological approaches, and the ongoing nature of the surveillance cohort.

References

  1. International Agency for Research on Cancer (IARC). Arsenic, metals, fibres, and dusts. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Vol. 100C (2012).
  2. Government of Canada. Asbestos (Updated 2020).
  3. Williams PRD, Phelka AD, Paustenbach DJ. A review of historical exposures to asbestos among skilled craftsmen (1940-2006). J Toxicol Environ Heal – Part B Crit Rev. 2007;10(5):319–77.
  4. Paustenbach DJ, Finley BL, Lu ET, Brorby GP, Sheehan PJ. Environmental and occupational health hazards associated with the presence of asbestos in brake linings and pads (1900 to present): A “state-of-the-art” review. J Toxicol Environ Heal – Part B Crit Rev. 2004;7(1):25–80.
  5. Jiang GCT, Madl AK, Ingmundson KJ, Murbach DM, Fehling KA, Paustenbach DJ, et al. A study of airborne chrysotile concentrations associated with handling, unpacking, and repacking boxes of automobile clutch discs. Regul Toxicol Pharmacol. 2008;51(1):87–97.