Sritharan J, Arrandale VH, Kirkham TL, Dakouo M, MacLeod JS, Demers PA.
Although several occupational exposures have been linked to the risk of COPD; limited data exists onsex-specifc diferences. This study aimed to identify at-risk occupations and sex diferences for COPDrisk. Cases were identifed in a large surveillance system established through the linkage of formercompensation claimants’ data (non-COPD claims) to physician visits, ambulatory care data, andhospital inpatient data (1983–2020). Cox proportional hazard models were used to estimate hazardratios (HRs) and corresponding 95% confdence intervals (CI) for occupation groups (occupation attime of claim), stratifed by sex. HRs were indirectly adjusted for cigarette smoking using anotherpopulation dataset. A total of 29,445 male and 14,693 female incident cases of COPD were identifed.Increased risks were observed in both sexes for construction (HRmale 1.15, 95% CI 1.12–1.19; HRfemale1.54, 95% CI 1.29–1.83) transport/equipment operating (HRmale 1.32, 95% CI 1.28–1.37; HRfemale1.53, 95% CI 1.40–1.68) farming (HRmale 1.23, 95% CI 1.15–1.32; HRfemale 1.19, 95% CI 1.04–1.37) andjanitors/cleaners (HRmale 1.31, 95% CI 1.24–1.37; HRfemale 1.40, 95% CI 1.31–1.49). Increased riskswere observed for females employed as chefs and cooks (HR 1.44, 95% CI 1.31–1.58), bartenders (HR1.38, 95% CI 1.05–1.81), and those working in food/beverage preparation (HR 1.34, 95% CI 1.24–1.45)among other occupations. This study demonstrates elevated risk of COPD among both male andfemale workers potentially exposed to vapours, gases, dusts, and fumes, highlighting the need foroccupational surveillance of COPD.
Keywords: COPD, Occupation, Sex diferences, Surveillance, Respiratory conditions.
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