Completed

Occupational cancer surveillance using the 1991-2006 Canadian Census Mortality & Cancer Cohort

Purpose

The goal of this project was to identify specific occupations, industries, or exposures that lead to an increased risk of cancer, by using a database containing information from the 1991 long form census linked to the Canadian Cancer Registry data. Relationships of interest include:

  • lung cancer in welders
  • occupations and ovarian cancer
  • cancer among wood workers
  • cancer among firefighters and police
  • shiftwork and cancer
  • cancer in agricultural workers
  • occupational physical activity and colorectal cancer

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Significance

There are approximately 60 well-established workplace carcinogens identified by the International Agency for Research on Cancer (IARC). However, there are over 100 industrial chemicals and other agents that are suspected to cause cancer, and many more have never been studied. Currently, Canada lacks any rapid, low cost means to assess whether there is an increased risk associated with an exposures, occupations or industries. The major challenge is that, although Canada registers every new cancer that is diagnosed, information on occupation and workplace exposures is not included in these records. Having a way to link occupation and industry data with data from the Canadian Cancer Registry would allow researchers to identify jobs or substances that carry an increased risk of cancer.

Methods

Statistics Canada linked data from the 1991 long form census to the Canadian Cancer Registry, a national database created with data from all the provincial and territorial tumour registries. The resulting database includes 2.7 million people. Analyses were undertaken to identify at-risk groups by occupation and industry, and to examine risks associated with certain occupational exposures.

Implications

These analyses contribute to the recognition of causes of cancer that can then be targeted for prevention efforts.

Funding

Linkage of the 1991 census to the Canadian Cancer Registry was funded by the Canadian Institute for Health Information and Health Canada. Analyses were funded by a WSIB Research Advisory Council grant for 2012-2015.

Scientific Articles
  • Prostate cancer surveillance by occupation and industry: the Canadian Census Health and Environment Cohort (CanCHEC)

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  • Sedentary work and the risks of colon and rectal cancer by anatomical sub-site in the Canadian census health and environment cohort (CanCHEC)

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  • Cancer risks in a population-based study of 70,570 agricultural workers: results from the Canadian census health and Environment cohort (CanCHEC)

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  • Occupational variation in incidence of bladder cancer: a comparison of population-representative cohorts from Nordic countries and Canada

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  • Cancer Risks among Welders and Occasional Welders in a National Population-Based Cohort Study: Canadian Census Health and Environmental Cohort

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  • Prostate cancer and occupational exposure to whole-body vibration in a national population-based cohort study

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Research Team
OCRC
Jill MacLeod, Paul Demers (PI), Manisha Pahwa, Garthika Navaranjan, Linda Kachuri, Jeavana Sritharan
Ryerson University
Anne Harris
Cancer Care Ontario
Anna Koné
University of Tampere
Kishor Hadkhale
Trainees (University of Toronto)
Marcella Jones, Trevor Van Ingen, Eliane Kim
Collaborators
Statistics Canada
Michael Tjepkema
Statistics Canada
Paul Peters